Oligonucleotide & RNA-Based Therapeutics Platforms
Supporting siRNA, ASO, miRNA, saRNA, gapmers, morpholinos, and aptamers—we provide target engagement and selectivity assays, cellular uptake and endosomal escape studies, in vivo gene silencing efficacy models (liver, CNS, muscle, ocular, dermatological), and tissue distribution profiling. Our ADME capabilities include nuclease stability, protein binding, and metabolite identification for chemically modified oligonucleotides.